منابع مشابه
Recent Update on Osteoporosis
Osteoporosis is a condition of low bone mass which predisposes to fractures. This silently progressive metabolic bone disease is widely prevalent in India in both sexes and occurs at younger age than in western population. Rapid bone loss occurs in postmenopausal women due to hormonal factors. Indians have low bone density compared to Caucasians. High prevalence of vitamin D deficiency is a maj...
متن کاملUpdate in male osteoporosis.
CONTEXT Osteoporosis in men is becoming an increasingly important public health problem. One in five men over the age of 50 yr will suffer an osteoporotic fracture during their lifetime, and men who sustain fractures have an increased mortality risk. EVIDENCE ACQUISITION Evidence was obtained by PubMed search and author's knowledge of the field. EVIDENCE SYNTHESIS Studies using computed qua...
متن کاملBiol. Pharm. Bull. 28(10) 2019—2022 (2005)
their excellent safety profile, despite their low transgene expression efficiency in comparison to that of viral vectors. For their administration, cationic lipid-mediated transfer is a promising approach, because of its low toxicity, ease of preparation, and potential for active targeting. One disadvantage associated with the use of DNA–cationic lipid complexes systemically is the induction of...
متن کاملUpdate on postmenopausal osteoporosis management.
One in two women has a fracture after the age of 50;1 most will be osteoporotic. Fracture incidence will probably increase as people live longer. After hip fracture there is 20% mortality within three months2 and increased disability, with >50% of people who previously walked unaided needing aids and >50% requiring help at home.3 Morbidity, disability and dependence increase progressively with ...
متن کاملUpdate in osteoporosis and metabolic bone disorders.
Considerable progress has been made in the development and testing of agents to treat osteoporosis. Most impressive are reports on new antiresorptive agents--both bisphosphonates (ibandronate and zoledronic acid) and monoclonal antibodies (MAbs) (denosumab) directed against receptor activator of nuclear factor kappaB-ligand, a key molecule in the control of commitment and activation of osteocla...
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ژورنال
عنوان ژورنال: the Singapore family physician
سال: 2019
ISSN: 0377-5305,0377-5305
DOI: 10.33591/sfp.45.7.ur